IONS

Ionis Pharmaceuticals Inc
NASDAQHEALTHCAREBIOTECHNOLOGY

Key Statistics

Market Cap
$12.49B
P/E Ratio
EPS
$-2.01
Beta
0.38
52W High
$86.74
52W Low
$32.00
50-Day MA
$74.25
200-Day MA
$72.18
Dividend Yield
Profit Margin
-30.90%
Forward P/E
90.91
PEG Ratio
25.70

About Ionis Pharmaceuticals Inc

Ionis Pharmaceuticals, Inc. discovers and develops RNA-targeted therapies in the United States. The company is headquartered in Carlsbad, California.

Official WebsiteUSAFY End: December

Fundamentals

Revenue (TTM)$1.06B
Gross Profit (TTM)$115.73M
EBITDA$-338.65M
Operating Margin-47.70%
Return on Equity-67.60%
Return on Assets-7.03%
Revenue/Share (TTM)$6.55
Book Value$2.96
Price-to-Book25.41
Price-to-Sales (TTM)11.80
EV/Revenue11.92
EV/EBITDA135.77
Quarterly Earnings Growth (YoY)-43.70%
Quarterly Revenue Growth (YoY)87.00%
Shares Outstanding$165.26M
Float$163.98M
% Insiders0.61%
% Institutions107.19%

Historical Volatility

HV 10-Day
28.13%
HV 20-Day
26.74%
HV 30-Day
24.35%
HV 60-Day
29.02%
HV Rank
7.5%

Volatility is currently expanding

Analyst Ratings

Consensus ($100.92 target)
8
Strong Buy
11
Buy
5
Hold

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Data last updated: 5/25/2026